Current Clinical Trials
Would you like to know if you qualify for one of our current clinical trials? If so, then please register for one of our studies below. Your personal contact information will never be shared with anyone outside of TMA. We will remove your information from our database at any time you wish; just call us at (910) 833-1954. We look forward to speaking with you.
Current Clinical Trials at TMA
FLU Vaccine
Millions of people come down with influenza (flu) every year, and it affects people differently, but complications of flu include pneumonia, ear infections, sinus infections and worsening of chronic medical conditions such as CHF, asthma or diabetes. Scientists are working to create a more protective vaccine, and we are currently testing one here. By participating in this trial, you will be protected against the flu and help us test a new flu vaccine.
To join, you:
- must be 18 years or older
- must not have received your flu vaccine in the past 6 months
What to Expect:
- Length of the trial is approximately 6-12 moths
- Up to 4 clinical site visits
- Weekly communication via e-diary
- Compensation for time and travel of about $400
Fill out the volunteer form here if you’d like to be considered for the Flu Vaccine clinical trial.
FLU Vaccine
Millions of people come down with influenza (flu) every year, and it affects people differently, but complications of flu include pneumonia, ear infections, sinus infections and worsening of chronic medical conditions such as CHF, asthma or diabetes. Scientists are working to create a more protective vaccine, and we are currently testing one here. By participating in this trial, you will be protected against the flu and help us test a new flu vaccine.
To join, you:
- must be 18 years or older
- must not have received your flu vaccine in the past 6 months
What to expect:
- Length of the trial is approximately 6-12 months
- Up to 4 clinical site visits
- Weekly communication via e-diary
- Compensation for time and travel of about $400
Fill out the volunteer form here if you’d like to be considered for the Flu Vaccine clinical trial.
RSV Vaccine
Respiratory syncytial virus (RSV) is a common respiratory virus that infects the lungs and breathing passages. RSV causes about 177,000 hospitalizations and 14,000 deaths in those over 65 years of age annually in the U.S. It is also the second leading cause of significant respiratory tract illnesses in adults, only behind influenza. The purpose of this clinical trial is to assess the safety of an investigational vaccine aimed at preventing RSV infection in people over 60 years of age or older.
To participate, you must be:
- 60 years of age and older
- In good health
- Primarily responsible for self-care
What to expect:
- Length of the study is approximately 2 years
- 8 visits to the clinical site
- Brief communication via telephone, email, or text messages
- Compensation for time and travel is about $3000
Fill out the volunteer form here if you’d like to qualify for the RSV (Respiratory syncytial virus) Vaccine clinical trial.
FLU+RSV Vaccine
Fill out the volunteer form here if you’d like to participate in the FLU and RSV (Respiratory syncytial virus) Vaccine clinical trial.
TRIO TRIAL
Enrolling Adults Ages 50-75 Now:
A Clinical Trial Evaluating Investigational mRNA Vaccines for 3 Respiratory Viruses
We are seeking participants for the Trio P101 Trial, evaluating investigational messenger RNA (mRNA) vaccines for 3 respiratory viruses: seasonal influenza (commonly called flu), respiratory syncytial virus (RSV), and SARS-CoV-2 (the virus that causes COVID-19). All 3 can easily spread from person to person, and all 3 can more severely affect people over age 65.1-3
The Potential of mRNA Vaccines
Often, vaccines for viruses are made from a weakened or inactive version of the virus. However, the investigational vaccines in this trial (mRNA-1010, mRNA-1045, mRNA-1273.214, mRNA-1345, and mRNA-1230) are different. They are all mRNA vaccines. These investigational vaccines contain mRNA codes that teach the body’s immune system to recognize and protect itself from the targeted viruses. You cannot become infected with the viruses that cause flu, RSV, or COVID-19 by getting any of these investigational vaccines.
Fewer Injections With the Same Potential Protection
Some of the investigational vaccines in this trial are combination vaccines. Combination vaccines put 2 or more individual vaccines in 1 injection. Combination vaccines can potentially reduce the number of injections you need for protection against common viruses like flu, RSV, and COVID-19. The benefits of combination vaccines include fewer injections, less pain and discomfort, one-time protection, fewer visits to the doctor with less hassle and cost, and less time off from work or family activities. Combination vaccines have existed for several years. For instance, children routinely receive combination vaccines for measles, mumps, and rubella (MMR) and diphtheria, tetanus, and pertussis (DTaP).
Who Can Join?
This clinical trial is looking for adult participants. To join, you must be:
· 50 to 75 years of age
· In good health
· Fully vaccinated for COVID-19 (with or without a booster) for at least 4 months prior to joining the clinical trial
Other criteria may apply in order to be eligible.
What to Expect
The total length of participation in this clinical trial is about 13 months. Potential participants will have a screening visit to check whether they are eligible to participate. If you are eligible and choose to participate, you will have about 6 more in-person visits over the next 13 months.
Fill out the volunteer form here if you’d like to participate in the Trio clinical trial.
Lung & Colorectal Cancer Screening Study
This research study is now enrolling to see if it is possible to develop
a cancer screening test based on blood samples.
The study will use blood samples collected from volunteers
who are undergoing routine lung or colon screening.
The purpose of this research study is to collect blood samples and medical information to help in the development of a blood test that can screen for many cancers from a single blood draw. This is an experimental test which is still under development, the goal of this blood test is to help doctors find cancers early, potentially at a time when tumours are still small.
Researchers will look at markers in the blood that show up when cancer is just developing. These findings from the blood, your medical history and results from your routine cancer screening will be used to develop this cancer screening blood test.
Who can take part in this trial?
- Women and men aged between 49-85 years undergoing routine colonoscopy screening.
- Women and men aged between 50-80 years undergoing routine lung cancer screening.
- We are looking for about 75,000 participants from around the world.
Will I be paid to participate in this study?
- To thank you for your time for participating in this research study, you will receive $200 after every blood draw (50 mL of blood) that you provide.
- For each additional blood sample (50 mL of blood) you provide every year for the 4 years this study will last, you will receive an additional $200.
- You may be reimbursed for other reasonable costs associated with blood draw visits (for example, transportation, parking) to travel from your home to the blood draw laboratory or facility.
Fill out the volunteer form here if you’d like to participate in the Lung & Colorectal Cancer Screening Study.
COVID/FLU Combo Vaccine Study
The main focus for the study is to see if the new formulation will reduce shot burden for patients by giving simultaneous protection.
This is a 6 month study with 5 in person visits and 4 safety phone calls. There will be compensation for your time and travel.
In order to participate:
- Must be fully vaccinated for COVID with primary series (at least) and all doses received at least 120 days ago
Fill out the volunteer form here if you’d like to participate in the COVID/FLU Combo Vaccine Study.
SMOKING Cessation
Have you, or someone you know, tried to quit smoking cigarettes unsuccessfully? If so, you’re not alone. Research from the Centers for Disease Control (CDC) found that 70% of adult cigarette smokers in the United States wanted to quit, yet only 7% are successful in doing so.
Our team, and researchers from many clinical centers across the United States, are helping to evaluate an investigational therapy called cytisinicline in combination with behavioral support as a new smoking cessation therapy. The clinical study, know as ORCA-3 is a Phase III trial to evaluate the safety and efficacy of cytisinicline in adults who smoke ten or more cigarettes per day and have at least one unsuccessful quit attempt with or without therapeutic support.
To join, you must:
- Be 18 years or older
- Be a current daily cigarette smoker who smokes ten or more cigarettes per day and who intends to quit smoking
- Have failed at least one previous attempt to stop smoking with or without therapeutic support
- Be willing to set a quit date within 5-7 days of starting treatment
- Be willing to actively participate in the study’s smoking cessation behavioral support provided throughout the study
What to expect:
- Length of the study is approximately 6 months
- 18 in person visits to the clinical site
- Compensation for time and travel is about $2,125
Fill out the volunteer form here if you’d like to qualify for a Smoking Cessation clinical trial.
SMOKING Cessation
Have you, or someone you know, tried to quit smoking cigarettes unsuccessfully? If so, you’re not alone. Research from the Centers for Disease Control (CDC) found that 70% of adult cigarette smokers in the United States wanted to quit, yet only 7% are successful in doing so.
Our team, and researchers from many clinical centers across the United States, are helping to evaluate an investigational therapy called cytisinicline in combination with behavioral support as a new smoking cessation therapy. The clinical study, known as ORCA-3 is a Phase III trial to evaluate the safety and efficacy of cytisinicline in adults who smoke ten or more cigarettes per day and have at least one unsuccessful quit attempt with or without therapeutic support.
To join, you must:
- Be 18 years or older
- Be a current daily cigarette smoker who smokes ten or more cigarettes per day and who intends to quit smoking
- Have failed at least one previous attempt to stop smoking with or without therapeutic support
- Be willing to set a quit date within 5-7 days of starting treatment
- Be willing to actively participate in the study’s smoking cessation behavioral support provided throughout the study
What to expect:
- Length of the study is approximately 6 months
- 18 in person visits to the clinical site
- Compensation for time and travel is about $2,125
Fill out the volunteer form here if you’d like to qualify for a Smoking Cessation clinical trial.
Pneumococcal Vaccine
Pneumococcal Disease is an illness caused by certain germs (bacteria), called streptococcus pneumoniae. These germs can cause serious infections in the ears, nose, lungs, blood, or brain. The purpose of this clinical trial is to assess the safety of an investigational vaccine aimed at protecting adults against pneumococcal disease.
To join, you must be:
- 18 years and older
- Pneumococcal vaccine naïve
What to expect:
- Length of the study is approximately 6 months
- 2 visits to the clinical site
- 4 brief communications via telephone or e-diary
- Compensation for time and travel is about $400
Fill out the volunteer form here if you’d like to qualify for a Pneumococcal Vaccine clinical trial.
Non-Erosive Reflux Disease (NERD)
Colorectal Screening
COVID Booster Vaccine Study
We are looking for healthy participants 18+ to be a part of our COVID BOOSTER Vaccine trial. This trial is looking at a new formulation for the Covid booster at a lower dose with a longer expiration.
This is a 12 months study, 5 in-person visits and 4 phone calls throughout the duration of the study. There will be compensation for your time and travel.
Must have received 4 prior doses of Covid 19-mRNA vaccine (primary series + 2 booster shots) in order to participate.
Fill out the volunteer form here if you’d like to qualify for the COVID Booster Vaccine Study.
Obesity Study
This Phase 3 study evaluates the safety and body weight reduction with LY3437943 to treat participants who have obesity or overweight with at least one weight-related comorbid condition.
We are looking for participants 18+ who have a BMI • ≥27 kg/m2.
Fill out the volunteer form here if you’d like to qualify for the Obesity Study.
TYPE 2 Diabetes Study
Fill out the volunteer form here if you’d like to qualify for the TYPE 2 Diabetes Study.
Refer a Friend and Receive $100
We are offering a Refer-A-Friend Bonus! For every person you recommend that enrolls in a TMA study you will receive $100!*
We are currently seeking volunteers for the following studies:
Flu Vaccine, RSV Vaccine, Pneumococcal Vaccine, Smoking Cessation
To refer a friend or see if you qualify, please call 910-833-1954 or fill out a volunteer form here.
* The $100 referral payment will be made to your existing ClinCard at the time the referred patient enrolls into the trial. An enrolled patient is defined as a patient that successfully completes the screening and Day 1 visit. The referred patient’s information and study participation status will be kept confidential, and they will be made aware that someone referred them to the trial and that they may receive payment.
TMA’s areas of study include:
- ** COVID VACCIINES **
- Healthy Volunteers – Vaccines
- Age 65 and Older Volunteers – Vaccines
- Fatty Liver
- Actinic Keratosis
- Colorectal Cancer Screening Test
- Atopic Dermatitis (Eczema)
- Diabetic Gastroparesis
- Gout and Cardiovascular Disease
- Hepatitis C
- Hypertension
- Iron deficiency in chronic kidney disease
- Smoking Cessation
- Phosphate Binder
- Rosacea
- Psoriasis
- Ulcerative Colitis
- Warts
- Bowel Preparation for Colonoscopy
- Diabetes
- Obesity
- Acne
- NASH
- Iron Deficiency Anemia
- IBS (d)
- FLU
- RSV
Volunteer for a Clinical Trial

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